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About ingenious



We’re the only mouse model company to perform all service steps in the USA.

Established in 1998, ingenious targeting laboratory (ingenious) is a leading global provider of custom genetically modified mouse, rat, and rabbit models. Our trusted gene editing service is built on over two decades’ worth of successful animal model creation for investigators, organizations, and companies in 44 states and 28 countries. We establish and maintain strong client relationships and support, and ensure the highest quality of our products. Our clients retain full intellectual property rights to their projects and benefit from full confidentiality.

Drs. Jennifer Parla, Milen Kirilov, and Arielle Bryan are part of our team of scientific experts.

ingenious stands as one of the very first mouse gene targeting companies. Our models have been published in hundreds of journals including ScienceNature, and Cell, making us one of the most validated and trusted production companies in the industry. Our research clients return time and again, and refer their friends and colleagues for the service provided by ingenious.



History of ingenious targeting laboratory

ingenious targeting laboratory’s story began in the early 1990s. The founders worked as researchers in the same lab at Rockefeller University. During their time at Rockefeller, they developed custom atherosclerotic knockout mouse models for studying heart disease. In 1998, they founded ingenious targeting laboratory and still continue to work directly in the lab, oversee mouse model production, and also handle the operation and business side of things.

As ingenious targeting laboratory, we first settled in at the Long Island High Technology Incubator (LIHTI) at Stony Brook University, discussing and sharing ideas with other researchers and companies in that space. A little over 10 years later, we expanded and moved to a larger facility on Long Island with 20,000 square feet. We still work closely with Stony Brook’s Division of Laboratory Animal Resources (DLAR) to house many of our mice.

From our small beginnings as one of the very first mouse gene targeting companies in the world, we’ve grown and streamlined our model generation process. Today ingenious uses both traditional and cutting-edge technologies to design custom mouse lines for our clients globally.


Dedicated scientists are with you from start to finish.

Accelerated the Research of Over 900 Laboratories

Over 20 Years in Business

Over 2,500 Completed Projects


Trusted Precision: Exactly what you need, our experts make it happen.

Fast Timelines: Germline in less time than ever before.

Assured Quality: The quality you need, the value you seek.


Our emphasis has always been on delivering the highest quality product by utilizing the best technologies.

A better model is within reach.


Delivering models that have advanced the research of hundreds of laboratories worldwide, ingenious utilizes both embryonic stem (ES) cell and CRISPR/Cas9 based technologies. Some of the mouse models we create include: constitutive and conditional (loxP) knockout mouse models, knockin mouse models (point mutations, cDNAs, reporter genes, tags, etc), humanized mouse models, inducible/reversible gene expression mouse models, and targeted transgenic mouse models. Utilizing our proprietary technologies results in the production of sophisticated, next generation animal models that help advance our understanding of human disease.

Client Testimonials


Location

Our corporate headquarters and laboratories are located in Ronkonkoma, New York, U.S.A. We are fortunate to be surrounded by, and enjoy relationships with, world-class research institutions such as Stony Brook University, Cold Spring Harbor and Brookhaven National Laboratory. In addition, being located near New York City places us at a global hub of travel, providing us with a gateway to our clients across the U.S.A. and the world. Our convenient location also gives us the opportunity to bring top talent to the ingenious team.

Subscribe to the ingenious Newsletter.
View Current Job Openings in Gene Editing Services.

Our Guarantee

As part of our commitment to you, we guarantee delivery of your germline-confirmed F1 heterozygous mice. We achieve our guarantee by providing the following:

  • Best quality targeting vector constructs, ranging in sizes from plasmid to BAC.
  • Proprietary mouse ES cell lines that consistently and reliably transmit to germline.
  • Our own FLP ES cell technology for streamlined deletion of antibiotic selection cassette (e.g., NeoR or HygroR) without need for extra steps.

With our guarantee, you can be confident in knowing that you will receive the mice you need at the cost you agreed to.

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