Preclinical Services at ingenious targeting laboratory

In Vivo Mouse Models, Drug Efficacy, Molecular Biology

Ingenious targeting laboratory offers preclinical services using their Immuno-Oncology humanized mouse models to evaluate drug candidate effectiveness and safety. Catering to pharmaceutical enterprises, biomedical research institutes, and academic R&D centers worldwide, our services include non-GLP toxicology studies to minimize preclinical failure risks, comprehensive pharmacokinetic analysis, and phenotypic analysis such as blood testing, imaging, and gene expression studies. Additionally, we provide pharmacodynamics evaluations for various drug effects, including anti-inflammatory and antineoplastic agents. These services aim to support in vivo experiments, mechanism investigations, and molecular biological studies for new drug development.

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“I have been always very satisfied by the work done by ingenious targeting laboratory for my custom mouse projects.”– Cem Gabay, MD
University Hospitals of Geneva

Based on our extensive humanized mouse model repository, ingenious targeting laboratory offers preclinical services for your drug candidates of interest.  We aim to satisfy the study requirements of your in vivo experiments, mechanism investigation and molecular biological studies, and to confirm the effectiveness and safety of new drug(s).

This service applies to pharmaceutical enterprises, biomedical research institutes, new drug development centers, new drug R&D institutes at colleges and universities, and other organizations worldwide.

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Non-GLP Toxicology

Designing a proper non-GLP acute toxicology study can help minimize the risk of failure during preclinical studies to help you decide whether your program is suitable to advance forward.

Using our Immuno-Oncology humanized mouse models, we can help to evaluate drugs through a comprehensive analysis platform and test the physiological and pathological effects of drugs.

Pharmacokinetics

Non-clinical pharmacokinetic studies reveal the dynamic changes of drugs in vivo, obtain the basic pharmacokinetic parameters of drugs, and clarify the process and characteristics of drug absorption, distribution, metabolism and excretion (ADME).

We can help to provide support and services for pharmacokinetic research in the pre-clinical trial phase.

Phenotype Analysis

We can help to perform the following studies in our Immuno-Oncology humanized mouse models:

  • Blood cell and blood biochemical testing
  • CT image analysis
  • Pathological section and immunohistochemical analysis
  • FACS sorting and analysis
  • Detection of blood cytokines
  • Gene expression and protein analysis
  • Whole-body in vivo imaging and analysis
  • Metabolic analysis
  • Behavioral research.

Pharmacology & Pharmacodynamics

Based on our Immuno-Oncology humanized mouse model repository, our Company can help provide pharmacodynamics evaluation services including the evaluation of drugs for anti-inflammatory immunity, antineoplastic agent analysis, effects based on the cardiovascular, respiratory, and metabolic system, and more.