CRISPR Rat Models

Get your custom rat model in less time & with more certainty.

Our process ensures precise genome editing for faster germline transmission modifications compared to traditional methods. We offer custom CRISPR rat models, including conventional knockouts, conditional knockouts, reporter knockins, and humanized cDNA knockins, tailored to your research needs. Available in various rat strains like Sprague Dawley, Long Evans, Wistar, and Lewis, our models provide reliable and efficient solutions for your scientific questions.

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“We have worked with inGenious Targeting Laboratory, Inc. on a variety of conventional, conditional and knockin projects, and we are very impressed with how flexible their service was to our needs and expectations. We look forward to our continued success in generating different mouse models with iTL.”– Iannis Aifantis, PhD NYU School of Medicine

CRISPR Rat Models

What Types of CRISPR Rat Models Are Possible?

The types of custom rat models that we can make for you include standard conventional knockout, conventional knockout with reporter, and standard conditional knockout with loxP sites. Rat knockins that we can make include point mutation knockin, reporter gene knockin, and humanized cDNA knockin.

Conventional Knockout
Knockout/Reporter Knockin
Cre-conditional Knockout
Point Mutation Knockin
Reporter Gene Knockin
Humanized cDNA Knockin

Rat Strains Available

Gene targeting in diverse rat strains, including:

Sprague Dawley (outbred)

Long Evans (outbred)

Wistar (outbred)

Lewis (inbred)

Why Rat Models?

Rats have been used to model human disease for over a century within a broad range of science fields including neurobiology, cardiology, immunology and toxicology. Their size and physiological similarity to humans make them an ideal choice for many labs. For example, surgical manipulations can be performed on rats that are difficult or impossible with smaller rodents, and fewer animals are required to generate sufficient material for experiments. Previously it was difficult to genetically modify rats but these limitations have been overcome by the use of CRISPR technology.

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Certainty

The model you design is the model we deliver.

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